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BMAL1通过抑制铁灭症来缓解败血症诱导的AKI

Songyuan Yang1, Zehua Ye1, Wu Chen1

  • 1Department of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China.

International immunopharmacology
|September 20, 2024
PubMed
概括

过度表达的BMAL1 (大脑和肌肉ARNT-Like蛋白1) 通过减少铁亡,可以防止败血症引起的急性损伤 (AKI). 这涉及抑制YAP和Hippo通路,为AKI提供潜在的治疗策略.

关键词:
艾基 (AKI) 是一个人.在BMAL1中,铁性化 (ferroptosis) 是一种河马的路径 河马的路径炎症性 炎症性 炎症性

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