在患有晚期逆皮肉瘤的患者中使用息治疗
Olivia Monton1, Andrei Gurau2, Kimberly Kopecky3
1Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
The Journal of surgical research
|September 20, 2024
概括
在2004年至2020年期间,晚期逆皮质肉瘤 (RPS) 的息疗法使用率从2.6%增加到6.5%. 年龄,保险状况和疾病阶段等因素影响了其利用率,但整体率仍然很低.
科学领域:
- 在瘤学瘤学.
- 抚慰性护理是一种缓解性护理.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 先进的逆肌肉瘤 (RPS) 呈现出显著的发病率,往往需要息治疗.
- 晚期RPS的息护理的趋势和预测因素尚未得到充分理解.
- 息干预旨在控制晚期癌症的症状并改善晚期癌症患者的生活质量.
研究的目的:
- 在美国 (2004-2020年) 分析高级RPS的息治疗利用的时间趋势.
- 确定与接受高级RPS的息治疗相关的患者和设施级因素.
主要方法:
- 使用国家癌症数据库 (NCDB) 进行回顾性队列研究.
- 包括2004-2020年被诊断为晚期RPS (AJCC阶段III-IV) 的成年患者.
- 趋势分析和多变量逻辑回归以评估时间变化和息治疗使用的预测因素.
主要成果:
- 总共有6149名晚期RPS患者被确定;只有383人 (6.2%) 接受了息治疗.
- 息治疗的使用率从2004年的2.6%显著增加到2020年的6.5% (Ptrend < 0.001).
- 息治疗的预测因素包括年龄较大,诊断年龄较晚,缺乏保险,社区癌症计划,第四阶段疾病和狂宫肌肉瘤组织学.
结论:
- 在高级RPS中使用息疗法正在增加,但仍然很低.
- 对于晚期RPS患者的息治疗的认识和可访问性需要改进.
- 需要进一步的研究,以优化这群人群的息护理策略.
相关概念视频
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K
Tumor Immunotherapy
491
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
491
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K


