关于手掌筋膜炎和多关节炎综合征的最新情况:系统性审查
Xiao Ma1, Xing-Yu Li1, Jing-Wen Wang1
1Department of Dermatology, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, 100730, China.
Joint bone spine
|September 20, 2024
概括
棕筋膜炎和多关节炎综合征 (PFPAS) 是一种罕见的副瘤性疾病. 早期识别PFPAS症状有助于检测潜在的恶性瘤,以便及时进行拯救生命的治疗.
科学领域:
- 风湿病学和瘤学
- 副生长性综合征 副生长性综合征
背景情况:
- 棕筋炎和多关节炎综合征 (PFPAS) 是一种罕见的疾病,通常与恶性瘤有关.
- 了解其临床,实验室和成像特征对于早期诊断至关重要.
研究的目的:
- 要总结PFPAS患者的特征.
- 为了评估PFPAS的各种治疗方法的有效性.
主要方法:
- 在Scopus,Embase和PubMed的系统文献搜索到2023年12月.
- 对人口统计,临床,实验室和成像数据的分析.
- 审查治疗策略及其结果.
主要成果:
- 分析了121名患者;平均年龄为61.4岁.
- 常见的症状包括手部胀/加厚 (49.6%) 和疼痛 (41.3%).
- 恶性瘤检测的中位时间为4个月;中位生存期为13个月.
- 肌肉骨成像异常在超声波,MRI和骨扫描中超过80%.
- 化疗 (66.0%) 和手术 (79.2%) 显示出有效的反应;生物药物在两例中产生了部分缓解.
结论:
- PFPAS是一种罕见的副瘤综合征.
- 早期的症状识别可以导致恶性瘤的检测和及时干预.
- 及时诊断和治疗可能会改善患者的生存结果.
相关概念视频
Assessment of the Cardiovascular System III: Palpation
214
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
214
Assessment of the Abdomen III: Palpation
381
Palpation is a crucial tactile examination method for assessing abdominal organs and detecting conditions like tenderness, distention, masses, or fluid. It involves both light and deep palpation techniques, each serving specific diagnostic purposes. Light palpation helps identify tenderness and other surface-level indicators, while deep palpation locates and assess abdominal masses and organ boundaries. A skilled professional can gather valuable insights through palpation, including evaluating...
381


