使用内置的临床决策支持来改善酸盐补充实践:一个准实验性研究
Joint Commission journal on quality and patient safety
|September 20, 2024
概括
使用临床决策支持 (CDS) 的电子健康记录 (EHR) 干预措施显著减少了静脉注射 (IV) 酸盐过度使用在患有低酸血症的患者中. 这种有针对性的方法改善了护理,减少了不必要的IV补充超过50%.
科学领域:
- 临床信息学 临床信息学
- 药理学 药理学是指药理学的学科.
- 医院管理局 医院管理局
背景情况:
- 住院血清酸盐替代实践表现出显著的变化,导致过度使用.
- 电子健康记录 (EHR) 与临床决策支持 (CDS) 的干预可以标准化护理并减少不必要的治疗.
- 过度使用低酸血症纠正有助于增加医疗保健成本和潜在的患者伤害.
研究的目的:
- 在EHR系统中实施和评估CDS工具,以减少过度使用静脉 (IV) 补充剂.
- 根据既定的临床指导方针,指导临床医生采取适当的酸盐补充策略.
- 为了减少不必要的IV酸盐的发病率在一个大的安全网医疗保健系统.
主要方法:
- 改进了现有的EHR订单集,用于用CDS填充酸盐,并纳入基于严重性的指导和简化订单.
- 在EHR中实施最佳实践咨询 (BPA),以提醒临床医生,当IV被要求用于轻度/中度低度血症时,没有零人数 (NPO) 状态.
- 测量了主要结果:在没有NPO订单的轻度至中度低血症患者中,IV酸盐替代率 (1.0-1.9 mg/dL) 每1000个患者日.
主要成果:
- 在没有NPO订单的情况下,轻度至中度低度血症的IV酸盐替代减少了53.0% (从7.22到3.40每1000个患者日;p < 0.001).
- 同时,这个患者群体的口服酸盐替代剂增加了38.8% (每1000个患者日从6.39到8.87;p<0.001).
- 在患者酸盐水平≥2.0 mg/dL的IV和口服酸盐替代剂中也观察到显著的减少.
结论:
- 采用CDS的双边EHR干预有效地减少了在轻度至中度低度患者的住院IV酸盐替代53.0%的患者.
- 干预成功地将治疗模式转移到更合适的补充策略,在大型安全网环境中.
- 集成到EHR系统中的CDS工具对于优化临床实践和减少药物过度使用是有价值的.
相关概念视频
Antihypertensive Drugs: Potassium-Sparing Diuretics
473
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...
473
Renal Failure: Dose Adjustments
68
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
68
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
106
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
106
Clinical Trials
6.6K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
6.6K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
124
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
124


