老年人吞和认知大脑网络之间的相关性通过功能性MRI
Jie Wang1, Mengqing Zhang2, Hongmei Wen3
1Rehabilitation Center, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Journal of oral rehabilitation
|September 21, 2024
概括
认知障碍和消化障碍有共同的大脑区域,这些区域的活动与认知得分有负相关性. 这突显了吞困难和认知能力下降之间的潜在神经生物学联系.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 医疗成像医学成像
背景情况:
- 临床证据将吞功能 (吞障碍) 与认知联系在一起,但潜在的神经生物学机制尚不清楚.
- 老年人特别容易患上认知障碍和食障碍.
- 了解这种联系对于有效的诊断和治疗至关重要.
研究的目的:
- 通过功能磁共振成像 (fMRI) 来比较吞和认知任务期间的大脑激活模式.
- 为了确定参与两种功能的共享神经网络.
- 探索这些共同区域的大脑活动与认知表现之间的关系.
主要方法:
- 与任务相关的fMRI对13名健康的老年人 (年龄大于60岁) 进行.
- 参与者完成了吞 (加厚的水) 和认知 (Stroop Color Word Test) 任务.
- 分析包括一般线性模型 (GLM) 和大脑活动与认知得分 (MoCA) 之间的相关性.
主要成果:
- 在这两项任务中激活的常见大脑区域包括叶,小脑和额叶/叶.
- 这些共同区域的活动与蒙特利尔认知评估 (MoCA) 评分有负相关性.
- 在吞和认知任务之间观察到明显的前额叶激活模式.
结论:
- 吞和认知任务涉及重叠的大脑区域.
- 这些共同区域中的活动与认知功能有反向关系,这表明有共同的神经基础.
- 调查结果提供了关于失调-认知联系的见解,并为失调康复策略提供了信息.
更多相关视频
相关概念视频
Brain Imaging
219
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
219
Deglutition
1.7K
Swallowing, otherwise known as deglutition, facilitates the transport of food from the mouth to the stomach. It is a multifaceted process that involves both the tongue and the muscles of the throat and esophagus. Saliva and mucus aid in this process, which takes approximately 4 to 8 seconds for semi-solid or solid food and around 1 second for liquids or very soft food.
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
1.7K
Cognitive Development During Adulthood
66
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
66


