相关实验视频

Updated: Aug 9, 2026

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface

Published on: July 10, 2014

使用四级甲基酸盐 (K18 QAMS) 和K18功能化的填充剂的抗微生物硬假牙

Sara Bellusa¹, Lianrui Chu¹, Evelyn Fung¹

¹Department of Comprehensive Dentistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Journal of applied biomaterials & functional materials

|September 21, 2024

概括

添加四级甲基酸盐 (K18) 和K18功能化的填充剂到假牙再线材料中,增强了抗菌性质. 虽然材料性能仍然与商业产品相比,但需要进一步开发以减少水吸附.

科学领域:

生物材料科学生物材料科学
牙科材料牙科材料
抗菌剂抗菌剂抗菌剂

背景情况:

硬的假牙再线材料易受微生物殖民,导致口腔感染.
四级化合物以其抗微生物疗效而闻名.
将抗菌剂纳入假牙材料可以防止生物膜的形成.

研究的目的:

评估四级甲基酸盐 (K18) 和K18功能化填充剂 (K18-Filler) 对硬假牙再线材料材料的材料和抗菌特性的影响.
评估这些添加剂在假牙基础应用中作为抗菌剂的潜力.

主要方法:

甲基甲酸盐中的K18 (K18-MMA) 和K18-Filler在不同度中被纳入硬假牙再线材料 (KoolinerTM).
材料属性包括硬度,水友性 (接触角度),机械强度 (模块,最终横向强度) 和水吸附等被评估.
确定了对Streptococcus mutans,S. sanguinis和Candida albicans的抗微生物活性.

主要成果:

大多数K18改性材料的硬度和水友性与对照组相比相当.
K18-MMA和K18-Filler通常会增加模量,但会降低最终的横向强度.
特定配方 (15%和20%的K18-MMA与30%的K18-Filler) 对所有测试的微生物表现出显著的抗菌活性.
这些有效的抗微生物配方在早期显示出水吸附的增加,在8周后变得可比.

结论:

K18-MMA和K18-Filler作为硬假牙再线材料的抗菌添加剂具有前途.
开发的材料具有商业产品范围内的材料特性.
对关键的口腔微生物实现了显著的抗菌活性.
需要进一步的研究来优化配方并减轻水吸附增加.

关键词:

抗微生物药物抗微生物药物在K18 QAS中.候选症候群病是一种候选症.假牙线/牙连接线假牙的牙炎是一种牙炎.

更多相关视频

2-Methacryloyloxyethyl Phosphorylcholine Polymer Treatment of Complete Dentures to Inhibit Denture Plaque Deposition

2-Methacryloyloxyethyl Phosphorylcholine Polymer Treatment of Complete Dentures to Inhibit Denture Plaque Deposition

Published on: December 26, 2016

Impact of Fabrication Techniques and Polishing Procedures on Surface Roughness of Denture Base Resins

Impact of Fabrication Techniques and Polishing Procedures on Surface Roughness of Denture Base Resins

Published on: January 17, 2025

相关概念视频

Essential Minerals for Bone Health

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

Biofilms

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...