作为人类保留β-葡萄糖酶抑制剂的脱氧cyclophellitols的合成和生物评估

Yevhenii Radchenko1, Qin Su1, Sybrin S Schröder1

  • 1Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2333 CC, Leiden, The Netherlands.

概括

研究人员开发了新型环利醇亚齐里丁,作为人类保留β-葡萄糖酶的基于活动的探针. 这些探针可以对GBA3或GBA1/GBA2进行选择性检测,有助于对β-葡萄糖酶功能的研究.

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