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Updated: Jun 12, 2025

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening
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Published on: October 16, 2015

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药物与人类血清白蛋白之间的相互作用的计算分析

Muslum Yildiz1

  • 1Department of Molecular Biology and Genetics, Gebze Technical University, Kocaeli, Turkey.

Journal of molecular recognition : JMR
|September 21, 2024
PubMed
概括

这项研究通过计算分析了2990种FDA批准的与人血清白蛋白 (HSA) 相互作用的药物. 结果显示,药物-HSA相互作用有利于cavity-1,特定的氨基酸残留对结合亲和力和稳定性至关重要.

关键词:
在HSA中,HSA就是HSA.专辑蛋白 (albumin) 是一种停靠的对接方式药物相互作用 药物相互作用

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