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Updated: Jun 20, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

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全国精密瘤学试点研究:KOrean精密医学联网小组研究基于基因组变化的分子分析指导疗法在先进的固体瘤 (KOSMOS) KCSG AL-20-05

T-Y Kim1, S Y Kim2, J H Kim3

  • 1Department of Internal Medicine, Division of Hematology and Medical Oncology, Seoul National University Hospital, Seoul.

ESMO open
|September 21, 2024
PubMed
概括

一个全国性的下一代测序导向分子分析导向疗法 (MGT) 平台证明,对于晚期癌症患者来说是可行的. 中央分子瘤委员会 (cMTB) 成功将一半以上的患者与向治疗相匹配,显示出有希望的有效性.

关键词:
分子造型指导治疗的分子造型.分子瘤板是一个分子瘤板.精确瘤学 精确瘤学

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Tumor Progression02:07

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...