从骨干到腿部的体积和附肌肉质量来自商用3维光学身体扫描仪,用于疾病风险识别
Jonathan P Bennett1, Michael C Wong1, Yong En Liu1
1Department of Epidemiology, University of Hawai'i Cancer Center, 701 Ilalo St, Honolulu, HI, 96813, USA.
Clinical nutrition (Edinburgh, Scotland)
|September 21, 2024
概括
三维光学成像 (3DO) 准确估计干到腿体积比和尾瘦质量 (ALM),与代谢综合征 (MetS) 风险相关. 这种可访问的技术增强了对MetS和脆弱性的临床评估.
科学领域:
- 身体组成分析分析.
- 代谢综合征研究研究
- 医学成像技术 医学成像技术
背景情况:
- 干与腿部体积比率与代谢综合征 (MetS) 和死亡率有关.
- 减少尾肌肉量 (ALM) 表明营养不良和脆弱的风险.
- 双能X射线吸收计 (DXA) 是这些测量方法的传统但难以获得的方法.
研究的目的:
- 评估三维光学成像 (3DO) 干到腿体积比率是否与DXA类似的MetS风险相关.
- 探索3DO对ALM进行估计的能力,以提高可访问性.
- 提高3DO在MetS和脆弱性评估中的临床实用性.
主要方法:
- 招募了各种各样的参与者进行3DO和DXA扫描.
- 校准3DO干部和腿部的体积到DXA等价物.
- 在干到腿体积四分位数中分析了MetS风险和血液生物标志物.
- 使用交叉验证从3DO测量估计DXAALM.
主要成果:
- 3DO干到腿体积与MetS风险有显著的关联 (OR=3.3每SD增加).
- 干至腿部体积最高四分之一具有27.4倍更大的MetS风险.
- 3DO精确估计了ALM,与DXA高度相关 (r2=0.96).
结论:
- 经过对偏移进行调整后的3DO干部与腿部的比率与MetS风险和血液参数有显著的关联.
- 3DO在各种体型中提供精确而准确的ALM估计.
- 3DO增强了对MetS风险和低肌肉质量的临床评估.
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