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Updated: Jun 12, 2025

Analysis of Transforming Growth Factor ß Family Cleavage Products Secreted Into the Blastocoele of Xenopus laevis Embryos
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由细胞外矩阵受体dystroglycan调节蛋白质分解裂变的分子基础

Michael J M Anderson1, Amanda N Hayward1, Adam T Smiley1

  • 1Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA.

Structure (London, England : 1993)
|September 21, 2024
PubMed
概括

矩阵金属蛋白酶 (MMPs) 切割双甘氨酸,破坏双甘氨酸蛋白复合体 (DGC). 我们解决了dystroglycan结构,揭示了调节MMP裂变的新型机制,这对于理解肌肉衰竭至关重要.

关键词:
这是一个SEAL域名.双氨酸糖蛋白复合物是如何形成的一个ectodomain的流失.机械传导 机械传导肌肉发育不良 肌肉发育不良 肌肉发育不良调节的膜内蛋白质溶解.结构生物学结构生物学

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