脆弱性和细胞癌:将综合老年评估纳入共同决策中
Alessio Pecoraro1, Giuseppe Dario Testa2, Laura Marandino3
1Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Unit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.
脆弱性显著影响患有细胞癌 (RCC) 的老年人,影响预后和治疗. 老年人的评估对于个性化管理和改善这些患者的治疗结果至关重要.
科学领域:
- 老年瘤学 老年瘤学
- 尿道瘤学 尿道瘤学
- 临床老年病学 临床老年病学
背景情况:
- 虚弱,衰老综合征的弹性降低,显著影响老年人的预后和管理,特别是在手术和瘤护理.
- 老年人细胞癌 (RCC) 管理存在独特的挑战,因为潜在的脆弱性和减少的生理储备.
研究的目的:
- 审查老年患者诊断出质或RCC的脆弱性评估策略.
- 探索虚弱对诊断工作,治疗决策和临床结果的影响.
主要方法:
- 进行了叙事文献综述,重点关注脆弱性定义,评估工具及其在RCC的背景下在老年瘤学中的应用.
- 总结了关于虚弱的预后价值,其对治疗结果的影响以及潜在干预措施的研究.
主要成果:
- 脆弱性是一个重要的负面预后因素,影响局部和转移性RCC的管理决策.
- 像老年人查工具8 (G8) 和迷你COG这样的查工具可以识别需要综合老年人评估 (CGA) 的老年患者 (≥65岁).
- 由老年医生进行的CGA,有助于风险分层并指导个性化治疗途径,突出了老年医生在多学科瘤委员会中的重要性.
结论:
- 脆弱性是影响RCC老年患者管理和治疗结果的关键因素.
- 将老年医生纳入诊断和治疗途径,可以有效地查和评估脆弱性.
- 这种方法支持基于整体患者风险分层的个性化治疗决策,优化临床结果.
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