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针对前列腺特异性膜抗原 (PSMA) 的SIRT2抑制剂的设计,合成和生物评估

Junhui Yu1, Zhicheng Gu1, Chuang Zhang1

  • 1State Key Laboratory of Functions and Applications of Medicinal Plants, Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Provincial Key Laboratory of Pharmaceutics, School of Pharmacy, Guizhou Medical University, Guiyang 550004, China.

Bioorganic chemistry
|September 22, 2024
PubMed
概括

针对前列腺特异性膜抗原 (PSMA) 的新型SIRT2抑制剂对前列腺癌治疗有希望. 化合物17显示增强的疗效和向前列腺癌细胞,克服了以前的抑制剂的局限性.

关键词:
这是一种抗癌药物.抑制剂的抑制剂在PSMA上,PSMA可以在PSMA上进行交易.前列腺癌是什么意思 前列腺癌是什么意思在SIRT2中,SIRT2是SIRT2.

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