有证据表明,塞内卡病毒A在自然感染的母猪中垂直传播
Rejane Schaefer1, Danielle Gava1, Gabrielly E Bombassaro1
1Embrapa Suínos e Aves, Concórdia, SC, Brazil.
Virology
|September 22, 2024
概括
塞内卡病毒A (SVA) 可以从母猪传播给小猪,导致疾病. 这项研究证实了垂直传播,即使有母体抗体,也突出了疫情期间的风险.
科学领域:
- 兽医病毒学 兽医病毒学
- 动物病理学 动物病理学
背景情况:
- 塞内卡病毒A (SVA) 在猪中引起囊泡性疾病和新生儿损失.
- SVA主要通过口腔,鼻腔和便途径传播.
研究的目的:
- 调查疫情期间SVA的垂直和先天性传播.
主要方法:
- RT-qPCR,病毒隔离,测序和病毒中和试验.
- 分析母猪血清,囊泡液,大奶粉和牛奶.
- 对小猪血清和临床症状的检查.
主要成果:
- 母猪在分娩前表现出病毒性病;小猪在出生后24小时内具有高病毒载荷.
- 在产后母猪的胆乳和牛奶中发现了传染性SVA.
- 小猪中的母体抗体没有预防病毒病或临床疾病.
结论:
- 这些发现支持猪中塞内卡病毒A的垂直和先天性传播.
- 尽管存在母体抗体,但仍可能发生SVA传播.
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