相关实验视频

Updated: Aug 15, 2026

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
08:59

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing

Published on: January 12, 2021

8.2K

在分散的大B细胞淋巴瘤中T细胞耗尽的基因调节机制基于单细胞转录组数据

Zhencang Zhou1, Pinwei Zhu1, Jinli Ge1

  • 1The First People's Hospital of Zunyi, Department of Hematology, The Third Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.

Leukemia research
|September 22, 2024
PubMed
概括

扩散性大B细胞淋巴瘤 (DLBCL) 显示T细胞疲劳增加,这种状态与不良结果有关. 这项研究揭示了耗尽的T细胞中独特的分子特征和途径,确定ID3作为关键基因和潜在的治疗标.

关键词:
扩散性大B细胞淋巴瘤个人隐私信息网络分析PPI网络分析路径丰富分析的分析方法单细胞转录组学 单细胞转录组学T细胞耗尽的情况

更多相关视频

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice07:36

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

6.4K
Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells06:07

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells

Published on: March 28, 2025

212

相关概念视频

Receptor Downregulation in MVBs01:15

Receptor Downregulation in MVBs

Multivesicular bodies (MVBs) are mature endosomes that sort ubiquitinated proteins and then fuse with lysosomes to degrade the sorted proteins. Epidermal growth factor (EGF) and its receptor (EGFR) form a complex that can be internalized through endocytosis, sorted into an MVB, and later degraded.
The EGFR can initiate signaling pathways that  lead to cell proliferation, migration, and differentiation. Overexpression of EGFR  stimulates cells to proliferate. Excessive  EGFR activation may...