在体外通过植物提取物抑制胚囊物种的生长
Shahira Abdelaziz Ali Ahmed1, Chad Schou2, Amira Bakr Mokhtar1
1Department of Medical Parasitology, Faculty of Medicine, Suez Canal University, Ismailia, 415221, Egypt.
Microbial pathogenesis
|September 22, 2024
概括
皮托洛斯泰蒙 (Ptilostemon chamaepeuce) 是一个小物种. 树提取物显示出强烈的抗母细胞囊活性,与甲尼达可比. 这种有前途的草药有效地减少了Blastocystis sp. 细胞大小,并导致体外形态变化.
科学领域:
- 寄生虫学的寄生虫学
- 自然产品化学 自然产品化学
- 传染性疾病 传染性疾病
背景情况:
- 布拉斯托西斯 (Blastocystis) 的物种 (种类) 是人类和动物常见的胃肠道前列腺体.
- 来自植物的天然产品正在被探索,作为潜在的治疗方法来治疗胚胎囊感染.
- 这项研究研究了三种特定的草药乙醇提取物的抗母细胞囊活性.
研究的目的:
- 评估Odontites linkii亚种体外抗母细胞囊活动. 塞浦路斯,Ptilostemon chamaepeuce 亚种. 这种类型的树种. cyprius,以及Quercus alnifolia的乙醇提取物. 这两种类型的提取物.
- 为了比较这些草本提取物对不同细胞囊亚型的疗效.
- 评估草本提取物在Blastocystis sp.上的细胞毒性.
主要方法:
- 在体外三种Blastocystis sp.的分子亚型. 孤立的. 孤立的.
- 在24小时和48小时内使用不同度 (250-2000微克/毫升) 的草药乙醇提取物进行细胞毒性分析.
- 评估寄生虫数量,形态和细胞大小,以确定抗母细胞囊作用.
主要成果:
- 皮托洛斯泰蒙 (Ptilostemon chamaepeuce) 是一个小物种. cyprius (1000μg/mL) 对所有测试的细胞囊菌株表现出显著和一致的细胞毒性,与甲尼达可比.
- P. chamaepeuce亚种的抗母细胞囊作用. cyprius包括降低了寄生虫数量,形态变化和细胞大小的减少.
- 牙虫 (Odontites linkii) 是一种牙虫的亚种. cyprius显示出可变的细胞毒性,而Quercus alnifolia对所有细胞囊菌株无效.
结论:
- 皮托洛斯泰蒙 (Ptilostemon chamaepeuce) 是一个小物种. cyprius提取物是一种强效和有前途的新药,可以对抗Blastocystis sp. 在体外. 在体外.
- 对P. chamaepeuce亚种的进一步研究. cyprius可能会导致新的治疗方法,用于细胞囊感染.
- 这项研究强调了特定植物衍生化合物在对抗寄生虫感染方面的潜力.
更多相关视频
09:21Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.
Published on: February 15, 2019
10.5K
06:47Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
6.3K
相关概念视频
02:57Plant Tissue Culture
Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
01:59Plant Breeding and Biotechnology
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
01:56Plant Hormones
Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands.
02:02Responses to Salt Stress
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
02:26Defenses Against Pathogens and Herbivores
Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
02:50Transgenic Plants
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...