在分娩的患者中,紧急和非紧急输血的风险因素分层
Douglas S Richards1, Sarah J Ilstrup2, M Sean Esplin1
1Intermountain Health, and the University of Utah Division of Maternal Fetal Medicine (Richards, Esplin, and Dizon-Townson), Salt Lake City, Utah, USA.
American journal of obstetrics & gynecology MFM
|September 22, 2024
概括
母亲出血风险分层是关键的. 大多数患者不需要输血,这使得血液制备方案更简单,成本更低.
科学领域:
- 产科和妇科 产科和妇科
- 输血医学 输血医学
- 医疗保健管理的管理
背景情况:
- 孕产妇出血是导致疾病的主要原因.
- 当前的输血准备指南通常基于危险因素,而不是输血概率.
- 对于所有分娩的例行血液制备的成本效益是可疑的.
研究的目的:
- 量化入院风险因素对输血需求的重要性.
- 为个体患者输血风险评估制定一个公式.
- 根据风险来告知适当的初始血液制备水平.
主要方法:
- 在18家医院进行了89,881次分娩的回顾性队列研究.
- 提取出血风险因素和输血准备水平.
- 输血的计算几率比率和患者特定的输血概率.
主要成果:
- 只有0.72%的患者接受过任何输血;0.35%需要紧急输血.
- 87.8%的患者有<1%的可能需要输血.
- 最高的输血风险与胎盘增殖谱,低入院血红蛋白和胎盘前期有关.
结论:
- 大多数患者需要输血的可能性非常低,尤其是紧急输血.
- 建议大多数患者使用"保持凝块"策略,为高危人群保留更广泛的准备.
- 实施这一战略可以显著降低医院的血液银行成本.
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