饮食中的糖和和脂肪消费与妊娠期间的胃肠道微生物组有关
Caitlin Dreisbach1, Tonja Nansel2, Shyamal Peddada3
1School of Nursing, University of Rochester, Rochester, NY, United States; Goergen Institute for Data Science, University of Rochester, Rochester, NY, United States.
怀孕期间的饮食质量会影响母亲的肠道微生物群. 特定的食物成分,如和脂肪和添加糖,与微生物组成和功能的变化有关.
科学领域:
- 微生物组研究的研究.
- 孕产妇健康 孕产妇健康
- 营养科学 营养科学
背景情况:
- 怀孕涉及显著的胃肠道微生物组变化.
- 这些微生物组变化可能会影响母亲和儿童的健康结果.
- 了解饮食在怀孕微生物组中的作用至关重要.
研究的目的:
- 研究饮食质量 (健康饮食指数 - HEI) 与母亲肠道微生物组之间的关联.
- 分析饮食对孕期微生物组成和功能基因本体学 (GO) 代表性的影响.
主要方法:
- 185名孕妇的回顾性分析 (怀孕饮食属性研究).
- 通过24小时回忆评估的饮食摄入量,计算HEI 2015.
- 第二个三个月的直肠拭子使用枪支测序进行分析;通过集群识别的肠型.
主要成果:
- 高质量的饮食与较低的早期怀孕BMI有关.
- 在高等教育机构得分和α多样性测量之间没有发现显著的关联.
- 特定的HEI成分 (和脂肪,添加糖,乳制品) 与不同的微生物种类和GO功能性肠型有关.
结论:
- 某些饮食成分与孕妇的肠道微生物组组成和妊娠中期的功能有关.
- 研究结果表明,特定的饮食干预可以调节妊娠微生物组.
- 结果为未来关于怀孕期间饮食与微生物群相互作用的研究奠定了基础.
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