母亲的社会剥夺和早产:PreCARE队列研究
Elsa Gottardi1, Elsa Lorthe1,2, Thomas Schmitz1,3
1Obstetrical Perinatal and Pediatric Epidemiology Research Team (EPOPé), Centre for Research in Epidemiology and Statistics (CRESS), Inserm, INRAE, Université Paris Cité, Paris, France.
Paediatric and perinatal epidemiology
|September 23, 2024
概括
这项研究发现,在法国PreCARE队列中,母亲的社会剥夺和早产风险之间没有联系. 社会因素并没有增加整体早产或特定表型的可能性.
科学领域:
- 产科和妇科 产科和妇科
- 社会流行病学 社会流行病学
- 围产期健康 围产期健康
背景情况:
- 母亲暴露于不利的社会条件与产周并发症有关,包括胎盘血管病理.
- 以前的研究表明,与社会因素相关的早产风险更高,但研究结果各不相同.
- 了解这些关联对于有针对性的干预至关重要.
研究的目的:
- 评估母亲的社会贫困和早产发病率之间的关系.
- 检查PTB整体和特定的表型,包括自发分娩,早产前膜破裂 (PPROM) 和胎盘血管病理.
主要方法:
- 分析了来自法国PreCARE队列研究的9365名参与者.
- 母亲的社会剥夺被定义为四个维度:社会隔离,不安全的住房,缺乏工作收入和缺乏标准医疗保险,结合成一个社会剥夺指数 (SDI).
- 逻辑-二项式和多项式回归模型被用于评估关联,根据母亲的年龄,平价,教育和出生地进行调整.
主要成果:
- 过早分娩发生在7.0%的怀孕中,自发分娩 (39.8%),PPROM (28.3%) 和胎盘血管病理 (21.8%) 是关键的表型.
- 在社会贫困指数 (SDI) 和早产总体风险之间没有发现统计学意义上的关联.
- 在多变量分析中,社会贫困的特定维度也没有显示出与PTB或其各种表型的显著联系.
结论:
- 该研究没有发现社会剥夺标志物与法国PreCARE队列中早产风险之间的关联证据.
- 这些发现表明,在这个特定的人群中,社会剥夺可能不是不同表型中早产的重要预测因素.
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