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Updated: Jun 12, 2025

Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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KEAP1-NRF2途径作为EGFR突变非小细胞肺癌的新疗法标

Jae-Sun Choi1, Hye-Min Kang2, Kiyong Na3

  • 1Clinical Research Institute, Kyung Hee University Medical Center, Seoul, Republic of Korea.

Tuberculosis and respiratory diseases
|September 23, 2024
PubMed
概括

抑制NRF2通路增强了细胞死亡和瘤生长抑制在EGFR突变肺癌耐药的TKIs. NRF2调制提供了一个新的策略来对抗TKI抵抗.

关键词:
布鲁萨托尔 (Brusatol) 是一种类型的药物.皮肤表皮生长因子受体.在KEAP1-NRF2路径中.电阻 电阻 电阻 电阻 电阻 电阻氨酸激酶抑制剂 氨酸激酶抑制剂

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