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异常脚臂指数对败血症存活率的影响:一年前性研究结果
Hsinyu Tseng1,2, Min-Tsun Liao1,2, Li-Ta Keng3,4
1Cardiovascular Center.
Acta Cardiologica Sinica
|September 23, 2024
概括
败血症患者的下肢外周动脉疾病 (LE-PAD) 与在一年内增加主要不良心血管事件 (MACE) 有关. 通过脚-手臂指数 (ABI) 的早期检测可以指导未来的心血管治疗血症幸存者.
科学领域:
- 心脏病学 心脏病学
- 关键护理医学 关键护理医学
- 血管医学 血管医学
背景情况:
- 下肢外周动脉疾病 (LE-PAD) 与不良的心血管结果有关.
- 未被诊断的LE-PAD,以异常的脚-手腕指数 (ABI) 表明,对在ICU中的败血症患者存活率的影响尚不清楚.
研究的目的:
- 调查异常ABI与重症监护室 (ICU) 败血症患者的结果之间的关联.
- 为了比较正常与异常ABI的败血症患者的死亡率和主要不良心血管事件 (MACE).
主要方法:
- 在ICU接受治疗的成人败血症患者的前性队列研究.
- 在ICU入院后24小时内获得的脚臂指数 (ABI) 测量.
- 在正常和异常ABI组之间比较30天和1年的全因死亡率和MACE发病率.
主要成果:
- 在102名败血症患者中,有37%的患者基于异常ABI的LE-PAD.
- 两组之间30天或1年死亡率没有显著差异 (分别p=0.56和p=0.24).
- 在1年的随访期间,在患有异常ABI的患者中,MACE的发生率显著更高 (21.1%对3.1%,p=0.003).
结论:
- 败血症患者的异常ABI与退院后一年内MACEs的增加有关.
- 需要进一步的研究来改善败血症幸存者的心血管结果.
- 临床试验.gov的标识符:NCT03372330.gov的标识符:NCT03372330.gov的标识符:NCT03372330.gov的标识符:NCT03372330.gov的标识符:NCT03372330.
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