针对COVID-19疫苗的RNA编辑:揭示了宿主免疫力的动态表观遗传调节

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CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery
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CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery

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Yun-Yun Jin1,2,3, Ya-Ping Liang1,2,3, Jia-Qi Pan1,2,3

  • 1Laboratory of Genomic and Precision Medicine, Wuxi School of Medicine, Jiangnan University, Wuxi, China.

Frontiers in immunology
|September 23, 2024
PubMed
概括

接种COVID-19疫苗会在血液中引发广泛的RNA编辑变化,影响免疫基因表达和功能. 这些动态变化是剂量依赖的,突出显示RNA编辑.

关键词:
一到一的RNA编辑.这是ADARs.这是COVID-19疫苗.这就是SARS-CoV-2病毒.免疫系统是免疫系统的.

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