维生素饮料提高了口感,并减少了与聚乙烯糖醇电解液溶液相关的不良事件
Lijie Huang1, Chunjian Li1, Yi-Zhou Jiang1
1Department of Gastroenterology, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, 29 Xinglong Lane, Tianning District, Changzhou, 213000, Jiangsu Province, China.
将维生素饮料 (Mizone) 添加到聚乙烯糖醇 (PEG) 肠道制剂中,可以显著改善味道并减少恶心. 患者更愿意重复改善的肠道准备进行结肠镜检查.
科学领域:
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
- 医疗器械 医疗器械
背景情况:
- 聚乙烯糖醇 (PEG) 溶液的不愉快味道阻碍了患者遵守结肠镜肠道准备.
- 有效的肠道清洁对于成功的结肠镜检查结果至关重要.
研究的目的:
- 为了评估将维生素饮料 (Mizone) 添加到4L分剂量PEG疗法中,以提高口感和患者舒适度的疗效.
- 评估Mizone对不良事件的影响以及患者愿意重复肠道准备过程的意愿.
主要方法:
- 进行了一项前性,单个内镜医生盲目的随机对照试验.
- 132名患者被随机分为两个组:PEG + Mizone (3.6L PEG + 0.4L Mizone) 和PEG (4L).
- 评估了可口性,不良事件,溶液消耗和愿意重复的意愿.
主要成果:
- PEG + Mizone组报告了显著更高的口味度得分 (4.00与2.95,p<0.001).
- 在PEG + Mizone组中,恶心的发生率较低 (9.1%与28.8%,p = 0.004).
- 完整溶液消耗 (95.5% vs. 78.8%,p = 0.004) 和愿意重复 (83.3% vs. 42.4%,p < 0.001) 显著高于Mizone.
结论:
- 将Mizone添加到PEG肠道制剂中可以提高口感和患者接受度.
- 这种辅助策略减少了恶心等不良事件,并增加了接受肠道准备的意愿.
- 修改后的治疗方案没有对电解质,血糖或功能水平产生不利影响.
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