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Updated: Jun 12, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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除了核糖体功能之外:RPS6缺乏通过破坏替代拼接来抑制胆管癌细胞生长

Wenkang Fu1, Yanyan Lin2, Mingzhen Bai1

  • 1The First School of Clinical Medicne, Lanzhou University, Lanzhou 730030, China.

Acta pharmaceutica Sinica. B
|September 23, 2024
PubMed
概括

核糖体蛋白S6 (RPS6) 在胆管癌 (CCA) 中被上调,促进癌症生长和不良预后. 用V-PMO向RPS6有效抑制了CCA的进展,提供了潜在的新治疗策略.

关键词:
另一个替代拼接.胆性瘤是一种胆性瘤.迷你染色体维护复杂组件 7 组件患者获得的有机体核糖体蛋白质S6 核糖体蛋白质S6活着的形态生物 (morpholino)在p53中,p53是什么?

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