Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

pV-Diagrams01:18

pV-Diagrams

4.0K
The pV diagram, which is a graph of pressure versus volume of the gas under study, is helpful in describing certain aspects of the substance. When the substance behaves like an ideal gas, the ideal gas equation describes the relationship between its pressure and volume. On a pV diagram, it is common to plot an isotherm, which is a curve showing p as a function of V with the number of molecules and the temperature fixed. Then, for an ideal gas, the product of the pressure of the gas and its...
4.0K
C4 Pathway and CAM01:27

C4 Pathway and CAM

45.3K
Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
45.3K
Interactions Between Signaling Pathways01:19

Interactions Between Signaling Pathways

6.2K
Signaling cascades usually lack linearity. Multiple pathways interact and regulate one another, allowing cells to integrate and respond to diverse environmental stimuli.
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
6.2K
ER Retrieval Pathway01:45

ER Retrieval Pathway

3.8K
In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...
3.8K
IP3/DAG Signaling Pathway01:11

IP3/DAG Signaling Pathway

11.9K
Membrane lipids such as phosphatidylinositol (PI) are precursors for several membrane-bound and soluble second messengers. Specific kinases phosphorylate PI and produce phosphorylated inositol phospholipids. One such inositol phospholipids are the  phosphatidylinositol-4,5 bisphosphate [PI(4,5)P2], present in the inner half of the lipid bilayer. Upon ligand binding, GPCR stimulates Gq proteins to turn on phospholipase Cꞵ. Activated phospholipase Cꞵ cleaves PI(4,5)P2 and...
11.9K
Indirect Motor Pathways01:22

Indirect Motor Pathways

1.4K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
1.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Optimizing COVID-19 vaccination strategies for high-risk populations: potential and challenges of combining heterologous boosting with respiratory mucosal delivery.

Frontiers in public health·2026
Same author

TRIM31: A Novel Guardian Against Periodontal Inflammation via Modulation of NLRP3 Inflammasome and Macrophage Polarization.

Immunological investigations·2026
Same author

Accuracy of the six-item cognitive impairment test for screening MCI among Chinese older adults with low educational attainment.

Aging & mental health·2026
Same author

Moving from "damage-centered" research to "family-centered" participatory action research for systems change: a call to action for developmental and family scientists.

Frontiers in psychology·2026
Same author

Protonation-Triggered Unlocking of Interlayer Carbon Nitride for Rapid Nanosheet Preparation.

Angewandte Chemie (International ed. in English)·2026
Same author

Divergent evolution of the PRPS enzymes across the tree of life.

bioRxiv : the preprint server for biology·2026
Same journal

Assessment of lower incisor position and symphysis dimensions among different skeletal patterns in the Chhattisgarh population.

Bioinformation·2026
Same journal

Low T3 syndrome and short-term outcomes in patients with acute decompensated heart failure: A retrospective observational study.

Bioinformation·2026
Same journal

Cardiovascular risk prevention awareness and practices in type 2 diabetes: Linking HbA1c and lipid levels.

Bioinformation·2026
Same journal

Assessment of periodontal condition using basic periodontal examination scores: A retrospective clinical study.

Bioinformation·2026
Same journal

Comparative evaluation of osseointegration among different surface modification techniques in dental implants.

Bioinformation·2026
Same journal

Micro-osteoperforations' impact on orthodontic tooth movement rate: Split mouth research.

Bioinformation·2026
查看所有相关文章

相关实验视频

Updated: Jun 12, 2025

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
05:01

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

Published on: July 1, 2020

3.2K

使用PAVER嵌入表示解读和可视化路径分析.

William G Ryan V1, Ali Sajid Imami1, Hunter Ali Sajid1

  • 1Department of Neurosciences, College of Medicine and Life Sciences, University of Toledo, Toledo, OH, USA.

Bioinformation
|September 23, 2024
PubMed
概括
此摘要是机器生成的。

奥米克研究产生复杂的途径数据. PAVER (路径分析可视化与嵌入表示) 通过分组相似的路径和识别基因组分析的代表性术语来简化解释.

关键词:
生物疗法是一种生物疗法.计算生物学是计算生物学.基因表达分析 基因表达分析路径分析 路径分析系统生物学 系统生物学

更多相关视频

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

17.5K
Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

2.1K

相关实验视频

Last Updated: Jun 12, 2025

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
05:01

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

Published on: July 1, 2020

3.2K
A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

17.5K
Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

2.1K

科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学

背景情况:

  • 奥米克研究产生了大量的高通量数据集,以了解生物特征和条件.
  • 解释由OMIC分析产生的漫长路径列表是一个重大挑战.
  • 需要有效的工具来将复杂的途径信息提炼成可操作的生物见解.

研究的目的:

  • 介绍PAVER (Pathway Analysis Visualization with Embedding Representations),这是一个用于大规模基因组分析的新型工具.
  • 为了应对从omics数据中解释广泛路径分析结果的挑战.
  • 提供直观的可视化和策划类似的途径,以增强生物理解.

主要方法:

  • PAVER使用矢量嵌入表示来基于相似性的集群路径.
  • 它通过对集群平均嵌入的等号相似性来确定每个集群中最具代表性的路径.
  • 该工具集成了多个路径分析,并支持任何路径数据库.

主要成果:

  • PAVER有效地将许多类似的路径整理成可管理的组.
  • 它为每个策划组确定了一个单一的,代表性的途径,简化了解释.
  • 该工具生成了通路关系的直观,准备发布的可视化图像.

结论:

  • 通过简化路径分析,PAVER提供了一个强大的解决方案来解释复杂的奥米克数据.
  • 该工具增强了从大型基因组研究中识别相关的生物学见解.
  • PAVER能够整合多种分析和数据库的能力使其成为研究人员的一种多功能资源.