通过抑制SMC3的表达和乙化,ZNF521促进了急性髓性白血病的发生

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Updated: Jun 12, 2025

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Rong Qin1, Tongshuo Yang1, Hongchao Jiang2

  • 1Hematologic Malignancy Group, Academy of Biomedical Engineering Research, Kunming Medical University, Kunming, 650500, PR China.

Heliyon
|September 23, 2024
PubMed
概括

指蛋白521 (ZNF521) 通过降低SMC3乙化来促进急性髓性白血病. 抑制ZNF521或其与HDAC8的相互作用为白血病提供了潜在的治疗策略.

关键词:
乙化 乙化是一种在 HDAC8 中,HDAC8 是在白血病中,白血病.在SMC3中,SMC3是SMC3.在 ZNF52121 中,

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