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Updated: Jun 12, 2025

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核因素红色素2相关因子2 (Nrf2) 在重金属引起的氧化应激中发出信号

Swapnil Tripathi1,2, Gitika Kharkwal1, Rajeev Mishra3

  • 1Toxicology Department, ICMR-National Institute of Occupational Health, Ahmedabad-380016, India.

Heliyon
|September 23, 2024
PubMed
概括

核因子红色素2相关因子2 (Nrf2) 途径可以抵御环境中毒物引起的氧化应激. 然而,这个系统可以悖论地促进金属诱导的致癌症与长时间的有毒元素暴露.

关键词:
细胞防御系统 细胞防御系统金属诱导的毒性金属诱导的毒性Nrf2-Keap1 信号传输系统氧化应激是一种氧化应激.有反应性氧物种的反应性氧物种.

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