探索分子农业在植物系统中治疗性和重组分子的最新进展
Jothi Kanmani Bharathi1, Preethika Suresh2,3, Muthu Arjuna Samy Prakash1
1Department of Genetics and Plant Breeding, Faculty of Agriculture, Annamalai University, Annamalai Nagar, 608002, Tamil Nadu, India.
Heliyon
|September 23, 2024
概括
分子农业使用转基因植物大规模生产药品,如重组蛋白和疫苗. 这种生物制药方法为传统方法提供了具有成本效益和可扩展性的替代方案,克服了当前生物制药生产的局限性.
科学领域:
- 生物技术是生物技术.
- 分子生物学分子生物学
- 制药科学 制药科学
背景情况:
- 基于蛋白质的药物由于其高疗效和安全性而变得越来越重要.
- 使用酵母,细菌和动物细胞的传统方法面临诸如高成本,复杂性和污染风险等局限性.
- 工厂为生物制药生产提供了一个有希望的替代方案,提供更低的成本和可扩展性.
研究的目的:
- 审查分子农业生产生物制药的技术可行性和有效性.
- 探索各种方法和方法,在植物系统中创造有价值的分子.
- 突出植物生物制药对传统表达系统的优势.
主要方法:
- 关于分子农业技术的现有文献的审查.
- 对用于异质蛋白表达的不同植物系统的分析.
- 评估植物生物制药的可扩展性和成本效益.
主要成果:
- 分子农业可以在工业规模生产重组蛋白质,抗体,酶,生长因子和疫苗.
- 基于植物的系统提供了显著的优势,包括降低生产成本和降低污染风险.
- 生物制药提供了更经济,更广泛的基本药物的供应.
结论:
- 分子农业是技术上可行和有效的方法,用于生产广泛的生物制药.
- 基于植物的生物制药是制药制造业的重大进步,解决了传统系统的局限性.
- 这种方法有望为各种疾病和公共卫生挑战提供更容易获得和负担得起的治疗方法.
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