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Updated: Jul 8, 2026

Using Enzyme-based Biosensors to Measure Tonic and Phasic Glutamate in Alzheimer's Mouse Models
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m6A阅读器YTHDC2通过调节星体细胞中SLC7A11依赖的谷氨酸失调来促进叶的病理生理学

Kai Zhang1,2, Zhiquan Yang1,2, Zhuanyi Yang1,2

  • 1Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.

Theranostics
|September 23, 2024
PubMed
概括

向天体细胞xCT和YTHDC2提供了一种新的治疗方法. 抑制这些蛋白质减少了谷氨酸,并控制了小鼠模型中的发作,显示了对抗药性的治疗潜力.

关键词:
是一种.谷氨酸的调节障碍 谷氨酸的调节障碍这是海马硬化症.m6A甲基化 的情况.反应性星球细胞的反应性星球细胞.

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Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...