激素治疗对勃起功能障碍患者主要心血管风险的影响 激素缺乏症患者
Tanawin Poopuangpairoj1, Kun Sirisopana1, Chinnakhet Ketsuwan1
1Division of Urology, Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Research and reports in urology
|September 23, 2024
概括
针对勃起功能障碍 (ED) 的替代疗法 (TRT) 在缺乏症患者中与正常水平患者相比,并没有增加主要的不良心血管事件.
科学领域:
- 心血管健康 心血管健康
- 内分泌学 在内分泌学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 勃起功能障碍 (ED) 是常见的,可以与缺乏症有关.
- 在ED患者中,替代疗法 (TRT) 的心血管安全性是一个重要的临床问题.
研究的目的:
- 评估接受TRT的ED患者与不接受TRT的患者的主要心血管不良事件 (MACE).
- 为了比较经过TRT的ED患者和没有丸激素缺乏症患者之间心血管事件的发生率.
主要方法:
- 在Ramathibodi医院从2012年1月到2021年10月的回顾性数据收集.
- 患有ED的患者被分为两组:TRT组和非TRT组 (正常丸激素水平).
- 重大心血管不良事件在治疗后2年被跟踪.
主要成果:
- 总共分析了221名患者 (111名TRT组,110名非TRT组).
- 非TRT组经历了一次心肌梗塞,一次过渡性缺血性发作和一次中风.
- 在2年的随访期间,TRT组中没有发生重大心血管事件;然而,两组之间没有发现显著差异 (p = 0.314).
结论:
- 在患有ED和缺乏症的男性中,替代疗法 (TRT) 似乎不会增加不良心血管事件.
- 当 TRT 给适当的 ED 患者时,心血管安全性得到维持,与具有正常丸激素水平的患者相比.
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