患者对演变性皮炎治疗的看法:评估患者愿意参加随机对照试验的评估
Annie Altman-Merino1, Kemberlee Bonnet2, David Schlundt2
1From the Department of School of Medicine, Vanderbilt University, Nashville, TN.
概括
大多数急性角膜炎患者会参加比较抗生素和安慰剂的试验,尽管对非抗生素治疗存在一些怀疑. 这项研究支持了这种临床试验的可行性.
科学领域:
- 胃肠病学 胃肠病学
- 临床试验 临床试验
- 患者的态度 患者的态度
背景情况:
- 抗生素是美国急性无并发性分泌体炎的标准,尽管有证据表明它们可能不必要.
- 随机试验将抗生素与安慰剂进行比较,可以加速采用无抗生素治疗.
- 医生对患者愿意参加此类试验存在担忧.
研究的目的:
- 评估患者对参加一次急性分炎随机试验的态度.
- 为了比较抗生素与安慰剂在治疗急性无并发性分泌体炎.
- 了解患者的感知和临床试验参与的决策因素.
主要方法:
- 一种混合方法的方法,将半结构面试和基于网络的调查结合起来.
- 采访探讨了患者的经验和试验的看法.
- 调查量化了参与意愿和关键影响因素.
主要成果:
- 在218名受访患者中,62%表示愿意参加随机临床试验.
- 参与的主要动机包括利他主义和科学贡献.
- 主要障碍涉及对仅观察治疗的疗效的怀疑.
结论:
- 患者对治疗急性无并发性分泌体炎的抗生素使用的看法各不相同.
- 大多数受访患者愿意参加抗生素与安慰剂试验.
- 结果表明试验可行性,并告知招聘策略.
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