一个隐蔽的淋巴瘤形:一个孩子的斯特里多
Rathakrishnan Venkatasamy1,2, Bee See Goh1,2, Rufinah Teo3
1Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MYS.
Cureus
|September 23, 2024
概括
这种案例研究突出了儿童淋巴细胞形 (LM),导致气道压缩和流. 赛洛斯治疗显著改善了斯特里多的症状.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 医学遗传学 医学遗传学
- 血管异常 血管异常
背景情况:
- 淋巴发育不良 (LM) 是一种先天性淋巴发育不良,通常与PIK3CA突变有关.
- 儿童的斯特里多可以由各种因素引起,头部和部瘤,包括LM,占不到3%的病例.
研究的目的:
- 报告儿科淋巴瘤形病例,该病例呈现出渐进的压力和气道压缩.
- 评估西洛斯治疗对管理由LM引起的气道阻塞的疗效.
主要方法:
- 一个两岁的男孩有渐进的噪音呼吸和度,经历了灵活的鼻喉镜和直接喉镜.
- 磁共振成像 (MRI) 证实了导致气道压缩的宏囊淋巴形.
- 开始治疗sirolimus治疗淋巴细胞形.
主要成果:
- 这位患者出现了吸入性流,并被诊断为一个压缩呼吸道的宏囊性LM.
- 核磁共振扫描显示了LM的程度,包括部和中上部.
- 经过1个月的西洛斯治疗后,观察到斯特里多的显著改善.
结论:
- 大型淋巴发育不良可能会导致儿童的呼吸道阻塞和气流,而部胀可能会在以后出现.
- 尽管非标签使用,西罗利斯治疗显示出高响应率 (91%) 和儿科LM的快速临床改善.
- 儿科斯特里多的非典型气道发现需要成像来排除像LM这样的质量的外部压缩.
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