相关实验视频

Updated: Jun 12, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

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在HPV阴性头部和部状细胞癌小鼠模型中的Smyd3介导免疫调节

Daniel E Tsai1, Alexei Lovanov2,3, Abdalla Abdelmaksoud2,3

  • 1Thoracic and GI Malignancies Branch, National Cancer Institute, Bethesda, MD 20892, USA.

iScience
|September 23, 2024
PubMed
概括

在口腔癌模型中,含有SET和MYND域的蛋白3 (SMYD3) 枯竭增强了抗PD-1疗法. 这项研究揭示了SMYD3的存在.

关键词:
细胞生物学 细胞生物学免疫学 免疫学 免疫学微观环境是一个微观环境.

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Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors

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In Vitro Establishment of a Genetically Engineered Murine Head and Neck Cancer Cell Line using an Adeno-Associated Virus-Cas9 System05:45

In Vitro Establishment of a Genetically Engineered Murine Head and Neck Cancer Cell Line using an Adeno-Associated Virus-Cas9 System

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相关概念视频

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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