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Updated: Jun 12, 2025

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激活ATM的扩散解释了γH2AX和MDC1在DNA损伤部位之外的扩散

Georgi Danovski1, Greta Panova2, Bradley Keister3

  • 1Institute of Molecular Biology, Bulgarian Academy of Sciences, 21, G. Bontchev Str, 1113 Sofia, Bulgaria.

iScience
|September 23, 2024
PubMed
概括

DNA修复涉及H2AX和MDC1.1的扩散酸化. 这项研究表明,虽然循环挤出是一个因素,但自由扩散的激活ATM (转基因突变的形膜炎) 也推动了这种传播,挑战了以前的假设.

关键词:
染色体组织组织分子生物学分子生物学核酸是核酸中的一种.

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