饮食炎症指数和头癌:伊朗的一个多中心病例控制研究
Saba Narmcheshm1,2, Monireh Sadat Seyyedsalehi2,3, Bahareh Sasanfar2,4,5
1Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Journal of research in health sciences
|September 23, 2024
概括
通过饮食炎症指数 (DII) 衡量的促炎症饮食与更高的头癌 (HNC) 风险有关. 这种关联在与烟草使用相结合时尤为强烈,强调了饮食在HNC发展中的作用.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 饮食因素影响癌症发生.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
- 了解饮食与HNC的联系对于公共健康至关重要.
研究的目的:
- 评估DII与头癌 (HNC) 风险之间的关联.
- 在HNC开发中研究DII和吸烟之间的相互作用.
- 为了检查伊朗人口中的这些关系.
主要方法:
- 一个多中心病例控制研究,涉及876个HNC病例和3409个对照.
- 通过130项食物频率问卷来评估饮食摄入量,以计算DII.II.
- 后勤回归分析用于确定DII第三方HNC的赔率比率 (OR),调整为混因素.
主要成果:
- 较高的DII分数 (促炎性饮食) 与增加的HNC风险相关 (OR T3与T1: 1.31).
- 在DII和唇腔/口腔癌 (OR T3与T1: 1.56) 和喉癌 (OR T3与T1: 2.08) 之间发现了显著的关联.
- DII和烟草使用之间的显著相互作用增加了HNC风险 (OR T3与T1: 2.52).
结论:
- 饮食炎症指数 (DII) 与头癌 (HNC) 风险有关.
- 促炎症饮食与唇部,口腔和喉癌的风险增加有关.
- 烟草使用和饮食中的炎症潜力在HNC发育上有显著的相互作用.
相关概念视频
Cancer Prevention
6.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.1K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
323
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
323
Inflammatory Bowel Disease II: Crohn's Disease
200
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
200
Gastritis-I: Introduction and Types
291
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
291
Inflammatory Bowel Disease I: Ulcerative Colitis
151
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
151
NF-κB-dependent Signaling Pathway
7.3K
The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The...
NF-κB-dependent Signaling Mechanism
The...
7.3K


