系统性右心室和双心室生理学患者的多模式成像和功能评估:一个回顾性单中心研究
Alice Pozza1, Martina Avesani1, Irene Cattapan1
1Pediatric Cardiology Unit, Department of Women's and Children's Health, University of Padua.
概括
患有TGA的患者的全身右心室功能障碍可以有效地使用心声回声学进行查,这与心脏磁共振成像良好相关. 已先天纠正的TGA患者表现出比心房切换手术后患者更好的心脏功能.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 系统右心室 (sRV) 功能障碍在患有先天性纠正的大动脉转移 (cc-TGA) 和大动脉右心血管转移 (D-TGA) 术后大动脉转移的患者中很常见.
- 迅速识别sRV功能障碍对于患者管理至关重要.
研究的目的:
- 为了比较心声和心磁共振 (CMR) 参数来评估sRV功能.
- 评估这些参数与临床变量和运动能力的相关性.
- 为了比较cc-TGA和D-TGA患者的心脏功能.
主要方法:
- 包括接受了标准,先进心声扫描 (包括3D和斑点跟踪) 和CMR (包括特征跟踪) 的CC-TGA和D-TGA后末/森宁手术的患者.
- 收集临床和成像数据.
- 对心声回声和CMR衍生的参数之间的相关性分析,以及临床变量,如峰值氧气消耗.
主要成果:
- 对sRV大小和功能的心声测量显示,与CMR衍生的体积和射出分数有很强的相关性.
- sRV全球纵向应变 (GLS) 与系统性心房应变 (sAS) 相对应.
- 系统性心房应变 (sAS) 是唯一与峰值氧气消耗相关的成像参数.
- 与D-TGA患者相比,CC-TGA患者表现出更好的GLS和更高的三环状平面缩外流 (TAPSE).
结论:
- 心声图是查sRV扩张和功能的有效工具,指导CMR的需要.
- 耳前变形成像可以增强对扩张功能的理解.
- 与心房切换后患者相比,CC-TGA患者表现出更好的心脏功能.
- 需要进一步的研究来确定与运动能力相关的成像参数.
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