解读下炎的表现和病因突出了重复系统性调查的需要
Lea Miquel1, Benoit Testud2, Frederique Albarel3
1Service de Médecine Interne et d'Immunologie Clinique, Hôpital de La Conception, Assistance Publique Hôpitaux de Marseille (AP-HM), 13005 Marseille, France.
The Journal of clinical endocrinology and metabolism
|September 23, 2024
概括
系统性原因在近一半的hypophysitis病例中被发现,在四分之一的患者中, pituitary疾病在系统性疾病之前. 这凸显了需要进行彻底的研究,以确定下炎的次要原因.
科学领域:
- 内分泌学 在内分泌学.
- 神经学 神经学
- 免疫学 免疫学 免疫学
背景情况:
- 低体质炎涉及垂体腺体和/或fundibulum的炎症.
- 了解低血清炎的各种病因对于患者的管理至关重要.
研究的目的:
- 描述低体质炎的初始表现和临床过程.
- 根据潜在的病因学来区分阴囊炎.
主要方法:
- 对被诊断患有阴囊炎的患者进行了回顾性观察性研究 (不包括与免疫检查点抑制剂相关的病例).
- 从2014年1月到2023年10月在大学推医院收集的数据.
- 包括15岁以上的患者.
主要成果:
- 包括61名患者;64%是女性,平均年龄为34岁.
- 常见的症状包括多尿多 (64%),头痛 (48%) 和喘息 (44%).
- 在91.5%和56%的病例中,分别存在下垂体缺陷 (前垂体或血管压素). 二次性低血清炎占46%的病例,其中瘤发病和朗格汉斯细胞囊细胞瘤是显著的原因. 在23%的二次病例中,垂体缺陷先于全身性疾病.
结论:
- 系统性病因占据了近一半的hypophysitis病例.
- 下垂体功能障碍可能会先于系统性表现,这强调了需要进行系统性调查的必要性.
- 重复的检查是必要的,以确定hypophysitis的二次原因.
相关概念视频
Gastritis-I: Introduction and Types
291
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
291
Gastritis-II: Pathophysiology
273
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
273
Hypersensitivities
550
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
550
Tonsillitis I: Introduction
212
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
212
Chronic Pancreatitis I: Introduction
76
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
76
Irritable Bowel Syndrome I: Introduction
255
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
255


