基于CT的纹理分析用于预测食道状癌的分化:一项观察性研究
Dawei Wang1, Zeyu Shang2, Rong Chen3
1Department of Thoracic Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
Medicine
|September 23, 2024
概括
计算机断层扫描 (CT) 的纹理分析可以预测食道状细胞癌 (ESCC) 的分化. 纹理参数如标准偏差和不均性有效区分瘤等级,有助于进行非侵入性手术前评估.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 食道状细胞癌 (ESCC) 的分化影响预后和治疗.
- 准确的手术前评估瘤分化对于治疗规划至关重要.
- 目前评估ESCC差异化的方法可能具有侵入性.
研究的目的:
- 评估计算机断层扫描 (CT) 纹理分析的可行性和临床价值,以预测ESCC差异化.
- 为了确定CT图像的纹理参数是否可以区分差异较差和中等差异较好的ESCC.
- 评估非侵入性CT纹理分析在手术前瘤分级方面的潜力.
主要方法:
- 从48名ESCC患者的胸部对比度增强CT扫描的回顾性分析.
- 根据病理学,患者分为差异化较差 (n=24) 和中等差异化较好 (n=24) 的两种分层.
- 使用FireVoxel软件对静脉相CT图像进行纹理分析,以提取标准偏差 (SD),不均性和等参数.
- 相关性分析和ROC曲线分析,以评估纹理参数的诊断性能.
主要成果:
- 在SD,不均质性,和ESCC差异化之间观察到负相关性 (P < .05).
- 不同质性显示出最强的相关性 (r = -0.505,P < .001).
- SD,不均质和显著区分差异较低和中等差异较高的ESCC (P < .05).
- ROC分析表明,SD (AUC=0.793) 和异质性 (AUC=0.792) 是差异化的最佳预测因素.
结论:
- 静脉相图的CT纹理分析是预测ESCC差异化的可行方法.
- 质地参数,特别是SD和不均性,可以非侵入性地评估瘤分化.
- 这种方法为手术前评估提供了有价值的工具,有可能指导ESCC的治疗策略.
相关概念视频
01:10Computed Tomography
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
01:14Imaging Studies I: CT and MRI
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
01:28Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
01:27Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...