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巴基斯坦的地区性结核病负担估计
Alvaro Schwalb1,2,3, Zia Samad4, Aashifa Yaqoob4
1TB Modelling Group, TB Centre, London School of Hygiene and Tropical Medicine, London, United Kingdom.
PLOS global public health
|September 23, 2024
概括
结核病 (TB) 的负担在巴基斯坦各地有很大差异.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染病建模 传染病建模
背景情况:
- 全球结核病 (TB) 负担估计通常是全国性的,掩盖了关键的次国家差异.
- 地方TB数据对于有针对性的政策制定和资源分配至关重要.
- 巴基斯坦国家结核病计划 (NTP) 寻求细粒度结核病负担估计,以改善公共卫生干预措施.
研究的目的:
- 用一个定制的工具估计巴基斯坦的地区性结核病负担.
- 确定结核病发病率最高,病例检测率最低的地区和省份.
- 在颗粒级别上为目标结核病预防和护理策略提供信息.
主要方法:
- 结核病国家级负担估计 (SUBsET) 工具被调整为巴基斯坦的地区级结构.
- 根据人口,城市化,住房和粮食不安全情况来加权地区.
- 国家结核病发病率数据使用150个地区的调查和通知数据进行了分配和改进.
主要成果:
- 据估计,结核病发病率在各地区各不相同,从每10万人口中110到462人.
- 辛德省,开伯尔巴赫顿克瓦省和旁遮普省的结核病负担最高.
- 在大多数地区,病例检测率 (CDR) 低于70%,其中10个地区报告过多.
结论:
- 亚国家结核病发病率的显著异质性需要巴基斯坦采取细粒度的方法.
- SUBsET工具提供了一种透明的方法来估计次国家结核病负担.
- 研究结果支持量身定制的结核病预防和护理策略,改善资源配置和公共卫生结果.
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