在童年玻璃眼 glaucoma 眼皮表面疾病的比较研究
Abdelrahman M Elhusseiny1,2, Abid Haseeb3, Taher K Eleiwa4
1Department of Ophthalmology, Harvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR.
Cornea
|September 23, 2024
概括
与健康儿童相比,患有青光眼 (CG) 的儿童经历的眼表面疾病 (OSD) 和干眼疾病 (DED) 症状明显多. 青光眼药物加剧了这些情况,突出了对CG亚型的进一步研究的需要.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 儿童青光眼 (CG) 是一种严重的疾病,需要长期治疗.
- 眼表面疾病 (OSD) 是青光眼患者常见的并发症.
- 儿童CG对眼睛表面的影响尚不清楚.
研究的目的:
- 评估患有青光眼 (CG) 的儿童眼表面疾病 (OSD) 的患病率和严重程度.
- 为了比较患有CG的儿童的OSD症状和体征,与健康对照对比.
- 评估青光眼药物和手术对儿童眼表面健康的影响.
主要方法:
- 一项多中心,比较,横截面研究,涉及27名CG患者和42名健康对照.
- 数据收集包括青光眼的类型,治疗方法,前段检查和撕裂时间 (TBUT).
- 干眼病 (DED) 症状使用阿拉伯语SPEED问卷进行了评估.
主要成果:
- 患有CG的患者表现出显著更短的TBUT和更高的斑点上皮质侵蚀的流行率.
- 在患有CG的儿童中,观察到DED症状的严重程度和患病率增加.
- 每次额外降低绿眼的药物都与更糟糕的TBUT和眼睛表面干燥相关.
结论:
- 与健康儿童相比,患有CG的儿童的OSD和DED发病率明显高.
- 青光眼的治疗,特别是药物使用,对儿科患者的眼睛表面产生负面影响.
- 需要在特定的儿童青光眼亚型中对OSD进行进一步的研究.
相关概念视频
Glaucoma: Overview
528
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
528
Open Angle Glaucoma: Treatment
406
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
406
Angle Closure Glaucoma: Treatment
451
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
451


