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甲状腺激素作用的表观遗传调节在人类代谢功能障碍相关的脂肪肝炎中

Alison-Michelle Naujack1, Christin Krause1, Jan H Britsemmer1

  • 1Institute for Human Genetics, Department of Epigenetics & Metabolism, Center of Brain Behavior & Metabolism, University of Lübeck, Lübeck, Germany.

European thyroid journal
|September 23, 2024
PubMed
概括

微RNA-34a-5p和DNA甲基化可能会在代谢功能障碍相关的脂肪肝炎 (MASH) 中驱动甲状腺激素抵抗. 肝脏中的这些表观遗传变化可以解释MASH进展和降低甲状腺激素信号.

关键词:
通过DNA甲基化.表观遗传学是指表观遗传学.与代谢功能障碍相关的脂肪肝炎.这就是miRNAs.甲状腺激素 甲状腺激素

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