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Updated: Jun 12, 2025

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PU.1 通过 CSF1R 调节骨关节炎的进展在突细胞中

Tingting Wang1, Jiakai Wang2, Tao Sun2

  • 1Department of Gerontology, The First Hospital of China Medical University, Shenyang 110001, PR China.

Biochimica et biophysica acta. Molecular basis of disease
|September 23, 2024
PubMed
概括

骨关节炎 (OA) 的进展是由转录因子PU.1驱动的,该转录因子在突细胞中直接激活CSF1R. 这一发现揭示了OA的关键分子机制和潜在的治疗点.

关键词:
纤维细胞样同胞细胞 (FLS)巨细胞是一个巨细胞.分子机制的分子机制骨关节炎 (OA) 是一种同胞细胞是同胞细胞.转录因子PU.1 是一个转录因子.

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