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Updated: Jul 18, 2026

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
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在体外,SHIN-2 通过稳定氨酸氧甲基转移酶的活性位点循环,对 VanA 类型的抗胺素耐药的 Enterococcus faecium 产生强有力的活性

Hironori Hayashi1, Erika Saijo2, Kazushige Hirata3

  • 1Division of Infectious Diseases, International Research Institute of Disaster Science, Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

Archives of biochemistry and biophysics
|September 23, 2024
PubMed
概括

新型抗菌剂对于打击抗菌素耐药性 (AMR) 是至关重要的. (+) -SHIN-2,一种氨酸基甲基转移酶抑制剂,对抗无交叉耐药的抗万科胺素耐药细菌有前途,有助于新药设计.

关键词:
抗菌耐药性的抗菌耐药性药物开发 药物开发传染病 传染病是一种传染病.一个碳代谢的代谢.这是一种SHMT抑制剂.

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