住院成年人痴呆症的药理治疗策略:过去,现在和未来
1Department of Pharmacy and Health Systems Sciences, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts.
Seminars in neurology
|September 23, 2024
概括
住院成年人的痴呆症仍然很常见,尽管有预防策略. 目前的证据不支持药理疗法以更快地恢复或改善结果,除了ICU中的激动.
科学领域:
- 老年病的医生 老年病的医生
- 关键护理医学 关键护理医学
- 医院 医院 医疗 医疗 医疗 医疗
背景情况:
- 痴呆症经常发生在住院成年人中,导致诸如认知能力下降等不良结果.
- 由于其相关的症状和负面后果,有效的妄想治疗策略至关重要.
研究的目的:
- 审查目前关于治疗住院成年人妄症的药理干预措施的证据.
- 为了识别错觉治疗研究中的差距和挑战.
主要方法:
- 关于药理和非药理妄症治疗的当前文献和实践指南的审查.
- 对疗效的证据分析,以解决妄想,减少症状和改善结果.
主要成果:
- 多域,非药物捆绑是痴呆症的主要治疗方法.
- 有限的证据支持药理干预措施以更快地解决问题,减少症状 (除了激动症) 或改善医院后的结果.
- 德克斯梅德托米丁 (Dexmedetomidine) 已知用于治疗ICU中严重妄相关的激动症.
结论:
- 目前的指导方针不建议在大多数医院环境中进行常规药理治疗妄症.
- 未来的研究应该探索新的药理干预措施,并解决现有的研究挑战.
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