声刺激与药理学预防相结合,还是药理学预防单独用于术后恶心和吐 (PONV) 预防,用于腹腔镜腹部手术的患者:随机对照试验的研究方案
Junjie Chen1,2, Lu Che3, Quexuan Cui2
1Peking Union Medical College, Beijing, China.
这项研究调查了PC6针点的电神经刺激是否能在腹腔镜手术患者中预防术后恶心和吐 (PONV). 结果表明,声刺激有效地减少了PONV的发病率和严重程度.
科学领域:
- 麻醉学和外科手术期间的医学.
- 整合和补充医学是整合和补充医学.
背景情况:
- 手术后恶心和吐 (PONV) 是腹腔镜腹部手术后的常见并发症.
- 标准的药理学预防在完全预防PONV方面存在局限性.
研究的目的:
- 评估PC6针点的可穿戴声刺激与PONV预防的药物预防相结合的有效性.
- 为了比较这种综合方法与仅在腹腔镜手术的患者中进行药理学预防.
主要方法:
- 一项前性随机对照试验,涉及302名接受选择性腹腔镜手术的患者.
- 参与者被分配到声刺激加药理学预防或假刺激加药理学预防.
- 在PC6点进行声刺激,从手术前30分钟开始,直到PACU放出.
主要成果:
- 主要结局是PONV的发病率.
- 二次结局包括PONV严重程度,恶心/吐率和胃肠道恢复.
- 探索性结果评估了血液动力学参数,住院和康复指数.
结论:
- 这项研究旨在确定将PC6声刺激与标准护理相结合是否能改善PONV预防.
- 研究结果将为临床实践提供有关PONV管理的非药物辅助的信息.
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