在我们成年人中,生命的基本8和妊娠期糖尿病的风险之间的关系
Lu Qin1, Zhixing Fan2, Qian Shi3
1Department of Gynecology and Obstetrics, Maternal and Child Health and Family Planning Service Center of Enshi Tujia and Miao Autonomous Prefecture, Enshi, China.
概括
通过生活必需8 (LE8) 实现高心血管健康 (CVH) 显著降低妊娠糖尿病风险. 这种益处在患有糖尿病家族史的人群中尤为明显.
科学领域:
- 心血管健康 心血管健康
- 生殖健康 生殖健康
- 公共卫生 公共卫生
背景情况:
- 孕期糖尿病 (GDM) 对母亲和婴儿的健康构成风险.
- 生活必需品8 (LE8) 是对心血管健康 (CVH) 的综合测量.
- 了解影响GDM风险的因素对于预防策略至关重要.
研究的目的:
- 调查生活必需品8 (LE8) 评分与美国成年人患妊娠糖尿病 (GDM) 的风险之间的联系.
- 为了确定不同水平的CVH是否会影响GDM风险.
- 探索CVH和糖尿病家族史与GDM风险之间的潜在相互作用.
主要方法:
- 利用了来自国家健康和营养检查调查 (2007-2018) 的数据.
- LE8分数被分为低 (0-49),中等 (50-79) 和高 (80-100) 的CVH.
- 使用加权的多变量逻辑回归模型来评估LE8和GDM风险之间的关系,并对共变量进行调整.
主要成果:
- 总共有3,189名参与者被分析,GDM患病率为15.33% (低CVH),11.46% (中度CVH) 和7.71% (高CVH).
- 高CVH与GDM风险降低显著相关 (OR:0.49,95%CI:0.29-0.83).
- 在CVH和家族糖尿病史 (P=0.04) 之间发现了显著的相互作用,高CVH显著降低了家族糖尿病史患者的GDM风险 (OR:0.357,95%CI:0.176-0.724).
结论:
- 根据LE8测量,较高的心血管健康水平与妊娠糖尿病风险降低有关.
- 高CVH的保护作用特别明显在具有糖尿病家族病史的人群中.
- 这些发现强调了促进最佳心血管健康对于预防GDM的重要性.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Pathophysiology of Diabetes
900
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
900
Diabetes: Symptoms, Diagnosis, and Complications
516
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
516
Diabetes Mellitus: Overview and Type I Subtype
2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.5K
Carbohydrate Metabolism
10.9K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.9K
Oral Hypoglycemic Agents: Biguanides and Glitazones
182
Biguanides, particularly metformin (Glucophage), are insulin sensitizers that enhance glucose uptake, thereby reducing insulin resistance. Unlike sulfonylureas, metformin doesn't prompt insulin secretion, which helps to curb hypoglycemia risk. Metformin is beneficial in treating conditions like polycystic ovary syndrome due to its insulin-resistance reduction capability. The drug's primary action involves curtailing hepatic gluconeogenesis, a significant contributor to high blood...
182


