在口腔手术后,抗菌具有多好地控制微生物殖民?
1Department of Oral and Maxillofacial Surgery, College of Dentistry, Mosul University, Mosul, Iraq. omerwaleedmajid@uomosul.edu.iq.
Evidence-based dentistry
|September 23, 2024
概括
抗菌涂层可以减少口腔外科手术中的细菌保留. 然而,需要更多高质量的研究来证实它们的有效性和成本效益,与非涂层线相比.
科学领域:
- 在口腔外科手术.
- 传染病控制和控制传染病
- 生物材料是一种生物材料.
背景情况:
- 手术部位感染仍然是口腔外科手术中的一个问题.
- 抗菌涂层接提供了一个潜在的策略,以减轻微生物殖民.
- 关于它们在临床环境中的有效性的证据正在不断发展.
研究的目的:
- 系统地审查有关抗菌涂层在口腔外科手术中的抗菌活性现有的文献.
- 评估与其使用相关的临床结果.
- 发现当前研究中的差距.
主要方法:
- 在PubMed和Scopus数据库 (2013年1月 - 2023年5月) 中进行了全面的文献搜索.
- 包括研究口腔外科手术中抗菌涂层的人类临床研究.
- 数据的提取和合成遵循了PRISMA-ScR指南.
主要成果:
- 在2014-2019年间发表的五项研究 (三项RCT) 被纳入.
- 在三项研究中,涂有抗菌剂的 sutures,特别是那些含有 triclosan 或 chlorhexidine 的 sutures,显示了细菌数量的减少.
- 两项研究没有发现显著差异;由于方法差异和样本小,结果各不相同.
结论:
- 抗菌涂层具显示出在口腔外科手术中减少细菌保留的潜力.
- 当前研究中的方法限制和小样本大小阻碍了最终的结论.
- 需要高质量,大规模的RCT来确定疗效和成本效益.
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