心脏代谢指数和妊娠期糖尿病之间的关联:一个横截面研究
Minchun Chen1, Suqiang Xiong2, Jie Zheng1
1Department of Pharmacy, Xi'an No.3 Hospital, The Affiliated Hospital of Northwest University, Xi'an, 710018, China.
较高的心脏代谢指数 (CMI) 与孕妇妊娠期糖尿病 (GDM) 风险增加有关. 这一发现表明CMI可能是怀孕期间GDM的早期预测因素.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 孕产妇健康 孕产妇健康
背景情况:
- 心脏代谢指数 (CMI) 是糖尿病的新兴标志物.
- 关于CMI和妊娠期糖尿病 (GDM) 风险之间的关联存在有限的研究.
- 了解CMI在GDM中的作用对于孕产妇健康至关重要.
研究的目的:
- 调查CMI与发展GDM风险之间的关联.
- 探索CMI作为孕妇GDM的潜在早期预测因素.
主要方法:
- 使用国家健康和营养检查调查数据 (1999-2018) 进行横截面研究.
- 分析包括单变量和多变量逻辑回归,受限立方线 (RCS) 和子组分析.
- 分析了710名孕妇,其中113人被诊断为GDM.
主要成果:
- 在较高的CMI和GDM风险之间发现了显著的正相关性 (OR: 1.75,95%CI: 1.03-2.99).
- RCS分析显示CMI和GDM之间存在线性关系 (P<0.001).
- 在饮酒或吸烟的妇女和墨西哥裔美国妇女中观察到积极的关联.
结论:
- 升高的CMI是怀孕期间GDM发病率的重要预测因素.
- 作为GDM的潜在早期诊断工具,CMI需要进一步调查.
- 这项研究强调了CMI在管理怀孕期间心脏代谢风险方面的重要性.
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