益生菌和微生物群对神经系统和精神疾病的影响
Hadi Hossainpour1,2, Salman Khazaei3, Hassan Mahmoudi4,5
1Department of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Central nervous system agents in medicinal chemistry
|September 24, 2024
概括
益生菌可以通过影响微生物群-肠-大脑轴来改善儿童的神经行为症状. 然而,目前的证据不足以证实它们对神经和精神疾病的有效性.
科学领域:
- 神经胃肠病学 神经胃肠病学
- 微生物组研究 微生物组研究
- 精神病学流行病学 精神病学流行病学
背景情况:
- 肠道微生物群通过微生物群-肠道-大脑轴影响大脑和神经系统.
- 肠道微生物群的破坏与胃肠道和非胃肠道疾病有关.
- 益生菌,活的有益微生物,正在研究它们的治疗潜力.
研究的目的:
- 审查目前关于益生菌对神经和精神健康的影响的证据.
- 探索微生物群-肠-大脑轴在精神疾病中的作用.
- 评估益生菌在控制神经行为症状方面的有效性.
主要方法:
- 在PubMed,科学网,Scopus和谷歌学者中进行了全面的文献搜索.
- 包括专注于益生菌,微生物群-肠-大脑轴和神经/精神健康的同行评审文章.
- 该综述综合了与益生菌干预及其对神经行为结果的影响相关的发现.
主要成果:
- 将益生菌纳入饮食已经显示出增强儿童神经行为症状的潜力.
- 审查的研究表明,肠道健康和心理健康之间可能存在联系.
- 然而,现有的数据是有限的和不确定的关于最终的治疗效益.
结论:
- 益生菌在预防或治疗神经和精神疾病方面的潜力需要进一步研究.
- 需要更严格和更广泛的研究来确定益生菌在这种情况下的有效性和安全性.
- 微生物群-肠-大脑轴是心理健康领域新型治疗策略的有希望的目标.
相关概念视频
Disorders of the Nervous Tissue
1.1K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises...
1.1K
Irritable Bowel Syndrome I: Introduction
255
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
255
Physiology of Enteric Nervous System and Gut Health
234
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
234
What is a Nervous System?
96.4K
Overview
96.4K
Stress and Mental Health
84
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
84
Bulimia Nervosa
55
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
55


