相关实验视频

Updated: Jun 12, 2025

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies

Published on: August 11, 2023

口腔白血病的恶性转变:系统审查和全面的元分析

Liliana Aparecida Pimenta-Barros¹, Pablo Ramos-García², Miguel Ángel González-Moles²

¹Dental Sciences Graduate Program, Federal University of Espirito Santo, Vitoria, Brazil.

|September 24, 2024

概括

口腔白血病 (OL) 的恶性转变率为6.64%. 风险因素包括不均的病变,更大的尺寸,舌头位置,吸烟和上皮质发育不良. 早期发现和管理至关重要.

科学领域:

口腔医学是指口腔医学.
在瘤学瘤学.
皮肤病学皮肤病学

背景情况:

口腔白血病 (OL) 是一种潜在的恶性口腔疾病.
了解其恶性转变风险对于早期干预至关重要.

研究的目的:

为提供有关口腔白血病恶性转变的最新全球证据综合.
确定与OL恶性转变相关的关键风险因素.

主要方法:

在MEDLINE,Embase,Web of Science和Scopus数据库中进行全面的文献搜索.
来自55项研究的比例元分析,其中包括41,231例OL病例.
使用乔安娜·布里格斯研究所工具和子组分析进行偏见风险评估.

主要成果:

对OL的综合恶性转变比例为6.64%.
恶性转变的重要危险因素包括非均的病变 (RR=4.23),更大的大小 (RR=2.08),舌头侧边缘位置 (RR=2.09),吸烟 (RR=1.64),以及上皮质发育不良 (RR=2.75).
恶性转变率在不同时期没有显著变化.

结论:

口腔白血病带有恶性转变的重大风险.
特定的临床和组织学特征,如非均的外观,更大的尺寸,特定的位置,吸烟和上皮质发育不良等,显著增加了这种风险.

关键词:

恶性转变的恶性转变这是一个元分析.口腔癌是口腔癌的一种疾病.在口腔白血病.口腔潜在的恶性疾病.系统性审查系统性审查

更多相关视频

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples

Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples

Published on: July 29, 2017

相关概念视频

Mechanisms of Retrovirus-induced Cancers

Mechanisms of Retrovirus-induced Cancers

Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...